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Scientist II, Computational Biology at Biogen in Cambridge, MA

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Description

Summary
The RNA Biology and Functional Genomics group, within Translational Genome Sciences, is seeking a highly skilled and motivated scientist to join a dynamic team dedicated to understanding the molecular basis of and developing novel therapeutics for neurological disorders.
Job Description
The candidate will work independently and with other experimentalists, computational biologists, and statistical geneticists to further our understanding of how genetic variation and RNA metabolism impacts disease and to discover novel drug targets in this area. This is a laboratory based position for a scientist with hands-on molecular and cellular biology skills and experience with CRISPR/Cas9 engineering methods to study the effects of genetic variants on the transcriptome and proteome. The key elements for success are deep technical expertise, a passion for doing science, and ability to communicate effectively with molecular and computational scientists.
Effective use of disruptive technologies is at the heart of Biogen's strategy to discover and develop highly differentiated medicines. We are investing in translational biology, human genomics, digital technologies and advanced analytics to address scientific questions to support the discovery and development of the next generation of therapeutics.
Responsibilities
*Develop a program of research in the areas of RNA biology and functional genomics that will support Biogen's drug discovery efforts in neurology and rare genetic disease.
*Partner with members of Translational Genome Sciences, Discovery Research, and Clinical Development to identify key questions and priorities that functional genomics experiments can impact
*Deliver experimental results that help define therapeutic target strategy
*Identify opportunities for external collaborations that supplement internal resources and ensure RNA biology and functional genomics research is at the cutting edge

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Qualifications
Translational Genome Sciences is responsible for providing genetics and genomics expertise to the R\u0026D organization and specifically, applies human genetic and genomic discoveries to support Biogen's drug discovery research teams and clinical development programs.
*Proven expertise in molecular and cellular biology techniques, including CRISPR/Cas9 engineering, mammalian cell culture, and modern cloning techniques.
*Advanced experience with RNA assay and genomics approaches to solve biological problems.
*Demonstrated ability to work independently by designing, executing, and troubleshooting experiments
*Strong collaboration, organizational, and communication skills and an ability to work well in a team setting are required.
*Sharp ability to learn and adapt to work on new tasks and projects that he/she may not have worked on previously.
Education
Ph.D. in Molecular and Cellular Biology, Genetics, or Genomics, plus 5+ years postdoctoral or industry experience.
All individuals deserve the right to achieve their full potential. Accordingly, our company welcomes all job applicants, and we strive to provide all employees with equal opportunity for advancement. We will not tolerate any form of discrimination or harassment based on an individual's sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information, or any other basis protected by local government agencies or law.
As an employer of choice, we strive to:
Provide attractive employment opportunities for diverse candidates at all levels and in all segments of our organization
Pursue and maintain relationships with sources of diverse candidates, community organizations, and academic institutions
Comply with both the letter and the spirit of all applicable laws and regulations relating to nondiscrimination and affirmative action in employment
VEVRAA Federal Contractor
We Request Priority Protected Veteran and Disabled Referrals for all of our locations

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